InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: DNASE1L1

Summary

InnateDB Protein

IDBP-383559.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

DNASE1L1

Protein Name

deoxyribonuclease I-like 1

Synonyms

DNAS1L1; DNASEX; DNL1L; G4.8; XIB;

Species

Homo sapiens

Ensembl Protein

ENSP00000393346

InnateDB Gene

IDBG-91292 (DNASE1L1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.

Experimentally validated
Total	1 [view]
Protein-Protein	0
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004536	deoxyribonuclease activity
GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters

Biological Process

GO:0000737	DNA catabolic process, endonucleolytic
GO:0006308	DNA catabolic process

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR005135 Endonuclease/exonuclease/phosphatase
IPR016202 Deoxyribonuclease I

PFAM

PF03372
PF14529

PRINTS

PR00130

PIRSF

PIRSF000988

SMART

SM00476

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q5HY40

UniProt Splice Variant

Entrez Gene

1774

UniGene

Hs.401929

RefSeq

HUGO

HGNC:2957

OMIM

300081

CCDS

HPRD

02096

IMGT

EMBL

BX936347

GenPept