Version 5.4
Homo sapiens Gene: ARHGEF19
Summary
InnateDB Gene IDBG-91417.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ARHGEF19
Gene Name Rho guanine nucleotide exchange factor (GEF) 19
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000142632
Encoded Proteins
IDBP-91421
Rho guanine nucleotide exchange factor (GEF) 19
IDBP-371707
Rho guanine nucleotide exchange factor (GEF) 19
IDBP-371708
Rho guanine nucleotide exchange factor (GEF) 19
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Guanine nucleotide exchange factors (GEFs) such as ARHGEF19 accelerate the GTPase activity of Rho GTPases (see RHOA, MIM 165390).[supplied by OMIM, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:16197854-16212609
Strand Reverse strand
Band p36.13
Transcripts
ENST00000270747 ENSP00000270747
ENST00000449495 ENSP00000391145
ENST00000441785 ENSP00000414370
ENST00000478117
ENST00000478210
ENST00000471928
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005089 Rho guanyl-nucleotide exchange factor activity
GO:0005096 GTPase activator activity
GO:0005515 protein binding
Biological Process
GO:0032321 positive regulation of Rho GTPase activity
GO:0032956 regulation of actin cytoskeleton organization
GO:0035023 regulation of Rho protein signal transduction
GO:0042060 wound healing
Cellular Component
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028919
View Gene Order
ENSBTAG00000005670
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.591532
RefSeq NM_153213
HUGO
OMIM
CCDS CCDS170
HPRD 10659
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca