Version 5.4
Homo sapiens Gene: NECAP2
Summary
InnateDB Gene IDBG-91496.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NECAP2
Gene Name NECAP endocytosis associated 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000157191
Encoded Proteins
IDBP-91502
NECAP endocytosis associated 2
IDBP-371845
NECAP endocytosis associated 2
IDBP-371847
NECAP endocytosis associated 2
IDBP-479658
NECAP endocytosis associated 2
IDBP-475895
NECAP endocytosis associated 2
IDBP-477565
NECAP endocytosis associated 2
IDBP-483993
NECAP endocytosis associated 2
IDBP-478370
NECAP endocytosis associated 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene likely encodes a member of the adaptin-ear-binding coat-associated protein family. Studies of a similar protein in rat suggest a role in clathrin-mediated endocytosis. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:16440672-16460078
Strand Forward strand
Band p36.13
Transcripts
ENST00000337132 ENSP00000338746
ENST00000457722 ENSP00000407091
ENST00000443980 ENSP00000391942
ENST00000504551 ENSP00000424509
ENST00000486390
ENST00000504858 ENSP00000421867
ENST00000508680
ENST00000492095 ENSP00000427620
ENST00000459640 ENSP00000421335
ENST00000496239
ENST00000513161 ENSP00000423213
ENST00000509727
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006897 endocytosis
GO:0015031 protein transport
Cellular Component
GO:0005622 intracellular
GO:0005886 plasma membrane
GO:0005905 coated pit
GO:0016020 membrane
GO:0030125 clathrin vesicle coat
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028923
View Gene Order
ENSBTAG00000013282
Not yet available
Cross-References
SwissProt Q9NVZ3
TrEMBL
UniProt Splice Variant
Entrez Gene 55707
UniGene Hs.437385
RefSeq NM_001145278 NM_001145277 NM_018090
HUGO HGNC:25528
OMIM 611624
CCDS CCDS44067 CCDS173 CCDS44066
HPRD 07674
IMGT
EMBL AK001282 AK023545 AK024468 AK302227 AL137802 AL669962 BC017014 BC018914
GenPept AAH17014 AAH18914 BAA91598 BAB14605 BAB15758 BAG63581 CAH71454 CAI22843
RNA Seq Atlas 55707

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca