Version 5.4
Homo sapiens Protein: NECAP2
Summary
InnateDB Protein IDBP-371847.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NECAP2
Protein Name NECAP endocytosis associated 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000391942
InnateDB Gene IDBG-91496 (NECAP2)
Protein Structure
UniProt Annotation
Function Involved in endocytosis. {ECO:0000250}.
Subcellular Localization Cytoplasmic vesicle, clathrin-coated vesicle membrane {ECO:0000250}. Cell membrane {ECO:0000250}. Note=Colocalizes with AP-2 at the plasma membrane. {ECO:0000250}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0006897 endocytosis
GO:0015031 protein transport
Cellular Component
GO:0005622 intracellular
GO:0005886 plasma membrane
GO:0005905 coated pit
GO:0016020 membrane
GO:0030125 clathrin vesicle coat
Protein Structure and Domains
PDB ID
InterPro IPR012466 Adaptin ear-binding coat-associated protein 1 NECAP-1
PFAM PF07933
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NVZ3
PhosphoSite PhosphoSite-Q9NVZ3
TrEMBL
UniProt Splice Variant
Entrez Gene 55707
UniGene Hs.437385
RefSeq NP_001138749
HUGO HGNC:25528
OMIM 611624
CCDS CCDS44066
HPRD 07674
IMGT
EMBL AK001282 AK023545 AK024468 AK302227 AL137802 AL669962 BC017014 BC018914
GenPept AAH17014 AAH18914 BAA91598 BAB14605 BAB15758 BAG63581 CAH71454 CAI22843

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca