Version 5.4
Homo sapiens Gene: SLC10A3
Summary
InnateDB Gene IDBG-91687.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC10A3
Gene Name solute carrier family 10 (sodium/bile acid cotransporter family), member 3
Synonyms DXS253E; P3
Species Homo sapiens
Ensembl Gene ENSG00000126903
Encoded Proteins
IDBP-91689
solute carrier family 10 (sodium/bile acid cotransporter family), member 3
IDBP-91691
solute carrier family 10 (sodium/bile acid cotransporter family), member 3
IDBP-243324
solute carrier family 10 (sodium/bile acid cotransporter family), member 3
IDBP-243326
solute carrier family 10 (sodium/bile acid cotransporter family), member 3
IDBP-383720
solute carrier family 10 (sodium/bile acid cotransporter family), member 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene maps to a GC-rich region of the X chromosome and was identified by its proximity to a CpG island. It is thought to be a housekeeping gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Dec 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome X:154487306-154490690
Strand Reverse strand
Band q28
Transcripts
ENST00000369649 ENSP00000358663
ENST00000263512 ENSP00000263512
ENST00000393587 ENSP00000377212
ENST00000393586 ENSP00000377211
ENST00000453912 ENSP00000395702
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008508 bile acid:sodium symporter activity
Biological Process
GO:0006814 sodium ion transport
GO:0010033 response to organic substance
GO:0015711 organic anion transport
GO:0015721 bile acid and bile salt transport
GO:0032526 response to retinoic acid
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000032806
View Gene Order
ENSBTAG00000014333
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.522826
RefSeq NM_001142391 NM_001142392 NM_019848 XM_005277913 XM_006724848
HUGO
OMIM
CCDS CCDS14755 CCDS48195
HPRD 02418
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca