Version 5.4
Homo sapiens Protein: SLC10A3
Summary
InnateDB Protein IDBP-243324.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLC10A3
Protein Name solute carrier family 10 (sodium/bile acid cotransporter family), member 3
Synonyms DXS253E; P3;
Species Homo sapiens
Ensembl Protein ENSP00000377212
InnateDB Gene IDBG-91687 (SLC10A3)
Protein Structure
UniProt Annotation
Function The ubiquitous expression and the conservation of the sequence in distant animal species suggest that the gene codes for a protein with housekeeping functions.
Subcellular Localization Membrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 1 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008508 bile acid:sodium symporter activity
Biological Process
GO:0006814 sodium ion transport
GO:0015711 organic anion transport
GO:0015721 bile acid and bile salt transport
GO:0055085 transmembrane transport
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR002657 Bile acid:sodium symporter
IPR004710 Bile acid transporter
PFAM PF01758
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P09131
PhosphoSite PhosphoSite-P09131
TrEMBL Q5HY78
UniProt Splice Variant
Entrez Gene 8273
UniGene Hs.522826
RefSeq NP_001135864
HUGO HGNC:22979
OMIM 312090
CCDS CCDS14755
HPRD 02418
IMGT
EMBL BC004966 BX664739 CH471172 L44140 X12458
GenPept AAA92651 AAH04966 CAA30998 CAI43236 CAI43238 EAW72697 EAW72698 EAW72699

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca