Version 5.4
Homo sapiens Gene: BAI3
Summary
InnateDB Gene IDBG-91804.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BAI3
Gene Name brain-specific angiogenesis inhibitor 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000135298
Encoded Proteins
IDBP-91806
brain-specific angiogenesis inhibitor 3
IDBP-91808
brain-specific angiogenesis inhibitor 3
IDBP-586650
brain-specific angiogenesis inhibitor 3
IDBP-808449
brain-specific angiogenesis inhibitor 3
IDBP-808450
brain-specific angiogenesis inhibitor 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This p53-target gene encodes a brain-specific angiogenesis inhibitor, a seven-span transmembrane protein, and is thought to be a member of the secretin receptor family. Brain-specific angiogenesis proteins BAI2 and BAI3 are similar to BAI1 in structure, have similar tissue specificities, and may also play a role in angiogenesis. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:68635367-69389511
Strand Forward strand
Band q12
Transcripts
ENST00000370598 ENSP00000359630
ENST00000238918 ENSP00000238918
ENST00000546190 ENSP00000441821
ENST00000604969 ENSP00000474165
ENST00000603207 ENSP00000473827
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004888 transmembrane signaling receptor activity
GO:0004930 G-protein coupled receptor activity
GO:0005515 protein binding
Biological Process
GO:0007166 cell surface receptor signaling pathway
GO:0007186 G-protein coupled receptor signaling pathway
GO:0007218 neuropeptide signaling pathway
GO:0016525 negative regulation of angiogenesis
Cellular Component
GO:0005886 plasma membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000033569
View Gene Order
ENSBTAG00000015335
Not yet available
Cross-References
SwissProt
TrEMBL B7Z1K0 J3KMY8 S4R3D0
UniProt Splice Variant
Entrez Gene 577
UniGene Hs.13261
RefSeq NM_001704
HUGO HGNC:945
OMIM 602684
CCDS CCDS4968
HPRD 04064
IMGT
EMBL AK293560 AL035469 AL078598 AL133378 AL158051 AL160401 AL356117 AL359714 AL391807 AL589875
GenPept BAH11536
RNA Seq Atlas 577

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca