Version 5.4
Homo sapiens Gene: PMPCA
Summary
InnateDB Gene IDBG-92370.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PMPCA
Gene Name peptidase (mitochondrial processing) alpha
Synonyms Alpha-MPP; INPP5E; P-55
Species Homo sapiens
Ensembl Gene ENSG00000165688
Encoded Proteins
IDBP-92374
peptidase (mitochondrial processing) alpha
IDBP-383931
peptidase (mitochondrial processing) alpha
IDBP-383934
peptidase (mitochondrial processing) alpha
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 9:136410570-136423761
Strand Forward strand
Band q34.3
Transcripts
ENST00000371720
ENST00000371717 ENSP00000360782
ENST00000399219 ENSP00000416702
ENST00000444897 ENSP00000408393
ENST00000462616
ENST00000612553
ENST00000619192
ENST00000620412
ENST00000622209
ENST00000614402
ENST00000610649
ENST00000620895
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0004222 metalloendopeptidase activity
GO:0046872 metal ion binding
Biological Process
GO:0006508 proteolysis
GO:0006626 protein targeting to mitochondrion
GO:0008152 metabolic process
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0005615 extracellular space
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005759 mitochondrial matrix
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000026926
View Gene Order
ENSBTAG00000001353
Not yet available
Pathways
NETPATH
REACTOME
REACT_118595
Mitochondrial protein import pathway
REACT_17015
Metabolism of proteins pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.495471
RefSeq NM_001282944 NM_001282946 NM_015160
HUGO
OMIM
CCDS CCDS35180 CCDS65192
HPRD 07500
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca