Homo sapiens Gene: SORCS2
Summary
InnateDB Gene IDBG-9263.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SORCS2
Gene Name sortilin-related VPS10 domain containing receptor 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000184985
Encoded Proteins
sortilin-related VPS10 domain containing receptor 2
sortilin-related VPS10 domain containing receptor 2
sortilin-related VPS10 domain containing receptor 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 4:7192538-7742836
Strand Forward strand
Band p16.1
Transcripts
ENST00000329016 ENSP00000329124
ENST00000507866 ENSP00000422185
ENST00000511199
ENST00000505529 ENSP00000424194
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 5 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008188 neuropeptide receptor activity
Biological Process
GO:0007218 neuropeptide signaling pathway
Cellular Component
GO:0016020 membrane
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.479099 Hs.609952
RefSeq NM_020777
HUGO
OMIM
CCDS CCDS47008
HPRD 12099
IMGT
EMBL
GenPept
RNA Seq Atlas