Version 5.4
Homo sapiens Gene: FUT7
Summary
InnateDB Gene IDBG-93011.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FUT7
Gene Name fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
Synonyms FucT-VII
Species Homo sapiens
Ensembl Gene ENSG00000180549
Encoded Proteins
IDBP-93013
fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X antigens. The encoded protein can direct the synthesis of the E-selectin-binding sialyl-Lewis X moiety. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:137030174-137033010
Strand Reverse strand
Band q34.3
Transcripts
ENST00000314412 ENSP00000318142
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 2 [view]
Protein-DNA 8 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008417 fucosyltransferase activity
GO:0046920 alpha-(1->3)-fucosyltransferase activity
Biological Process
GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO:0002522 leukocyte migration involved in immune response
GO:0006486 protein glycosylation
GO:0036065 fucosylation
GO:0042355 L-fucose catabolic process
Cellular Component
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0032580 Golgi cisterna membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000036587
View Gene Order
ENSBTAG00000046516
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa00601
Glycosphingolipid biosynthesis pathway
hsa00514
Other types of O-glycan biosynthesis pathway
INOH
PID NCI
Cross-References
SwissProt Q11130
TrEMBL
UniProt Splice Variant
Entrez Gene 2529
UniGene Hs.457
RefSeq NM_004479
HUGO HGNC:4018
OMIM 602030
CCDS CCDS7022
HPRD
IMGT
EMBL AB012668 AK313124 AL807752 BC074746 BC086312 U08112 U11282 X78031
GenPept AAA20468 AAA56869 AAH74746 AAH86312 BAA32819 BAG35944 CAA54962 CAI12771
RNA Seq Atlas 2529

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca