Version 5.4
Homo sapiens Protein: FUT7
Summary
InnateDB Protein IDBP-93013.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FUT7
Protein Name fucosyltransferase 7 (alpha (1,3) fucosyltransferase)
Synonyms FucT-VII;
Species Homo sapiens
Ensembl Protein ENSP00000318142
InnateDB Gene IDBG-93011 (FUT7)
Protein Structure
UniProt Annotation
Function May catalyze alpha-1,3 glycosidic linkages involved in the expression of sialyl Lewis X antigens.
Subcellular Localization Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Note=Membrane-bound form in trans cisternae of Golgi.
Disease Associations
Tissue Specificity Leukocytic/myeloid lineage cells.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.
Experimentally validated
Total 10 [view]
Protein-Protein 2 [view]
Protein-DNA 8 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008417 fucosyltransferase activity
GO:0046920 alpha-(1->3)-fucosyltransferase activity
Biological Process
GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO:0002522 leukocyte migration involved in immune response
GO:0006486 protein glycosylation
GO:0036065 fucosylation
GO:0042355 L-fucose catabolic process
Cellular Component
GO:0005794 Golgi apparatus
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0032580 Golgi cisterna membrane
Protein Structure and Domains
PDB ID
InterPro IPR001503 Glycosyl transferase, family 10
PFAM PF00852
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q11130
PhosphoSite PhosphoSite-Q11130
TrEMBL
UniProt Splice Variant
Entrez Gene 2529
UniGene Hs.457
RefSeq NP_004470
HUGO HGNC:4018
OMIM 602030
CCDS CCDS7022
HPRD 03611
IMGT
EMBL AB012668 AK313124 AL807752 BC074746 BC086312 U08112 U11282 X78031
GenPept AAA20468 AAA56869 AAH74746 AAH86312 BAA32819 BAG35944 CAA54962 CAI12771

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca