Version 5.4
Homo sapiens Gene: DPP7
Summary
InnateDB Gene IDBG-93065.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DPP7
Gene Name dipeptidyl-peptidase 7
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000176978
Encoded Proteins
IDBP-93067
dipeptidyl-peptidase 7
IDBP-810966
dipeptidyl-peptidase 7
IDBP-810970
dipeptidyl-peptidase 7
IDBP-810972
dipeptidyl-peptidase 7
IDBP-810980
dipeptidyl-peptidase 7
IDBP-810985
dipeptidyl-peptidase 7
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is a post-proline cleaving aminopeptidase expressed in quiescent lymphocytes. The resting lymphocytes are maintained through suppression of apoptosis, a state which is disrupted by inhibition of this novel serine protease. The enzyme has strong sequence homology with prolylcarboxypeptidase and is active at both acidic and neutral pH. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 9:137110542-137115177
Strand Reverse strand
Band q34.3
Transcripts
ENST00000371579 ENSP00000360635
ENST00000470766 ENSP00000473354
ENST00000473532 ENSP00000473430
ENST00000463619 ENSP00000473309
ENST00000483783
ENST00000472306 ENSP00000473364
ENST00000485456
ENST00000460830
ENST00000482088
ENST00000478597
ENST00000497375 ENSP00000473618
ENST00000473703
ENST00000491807
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008236 serine-type peptidase activity
GO:0008239 dipeptidyl-peptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005764 lysosome
GO:0005829 cytosol
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000026958
View Gene Order
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_013379 XM_006717083
HUGO
OMIM
CCDS CCDS7030
HPRD 07634
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca