Version 5.4
Homo sapiens Protein: DPP7
Summary
InnateDB Protein IDBP-93067.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DPP7
Protein Name dipeptidyl-peptidase 7
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000360635
InnateDB Gene IDBG-93065 (DPP7)
Protein Structure
UniProt Annotation
Function Plays an important role in the degradation of some oligopeptides. {ECO:0000269PubMed:15487984}.
Subcellular Localization Lysosome {ECO:0000269PubMed:15487984}. Cytoplasmic vesicle {ECO:0000269PubMed:15487984}. Secreted {ECO:0000269PubMed:15487984}.
Disease Associations
Tissue Specificity Detected in seminal plasma (at protein level). {ECO:0000269PubMed:15487984}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008236 serine-type peptidase activity
GO:0008239 dipeptidyl-peptidase activity
Biological Process
GO:0006508 proteolysis
Cellular Component
GO:0005764 lysosome
GO:0005829 cytosol
GO:0016023 cytoplasmic membrane-bounded vesicle
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000073 Alpha/beta hydrolase fold-1
IPR008758 Peptidase S28
IPR029058 Alpha/Beta hydrolase fold
PFAM PF00561
PF05577
PRINTS PR00111
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UHL4
PhosphoSite PhosphoSite-Q9UHL4
TrEMBL
UniProt Splice Variant
Entrez Gene 29952
UniGene
RefSeq NP_037511
HUGO HGNC:14892
OMIM 610537
CCDS CCDS7030
HPRD 07634
IMGT
EMBL AF154502 AK292112 AL929554 BC011907 BC016961
GenPept AAF12747 AAH11907 AAH16961 BAF84801 CAH72872

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca