Version 5.4
Homo sapiens Gene: LYPLA2
Summary
InnateDB Gene IDBG-94007.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LYPLA2
Gene Name lysophospholipase II
Synonyms APT-2; DJ886K2.4
Species Homo sapiens
Ensembl Gene ENSG00000011009
Encoded Proteins
IDBP-94009
lysophospholipase II
IDBP-94013
lysophospholipase II
IDBP-94015
lysophospholipase II
IDBP-94017
lysophospholipase II
IDBP-94019
lysophospholipase II
IDBP-375049
lysophospholipase II
IDBP-375052
lysophospholipase II
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. There are alternatively spliced transcript variants described for this gene but the full length nature is not known yet. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:23790970-23795539
Strand Forward strand
Band p36.11
Transcripts
ENST00000374514 ENSP00000363638
ENST00000374505 ENSP00000363629
ENST00000374503 ENSP00000363627
ENST00000374502 ENSP00000363626
ENST00000374501 ENSP00000363625
ENST00000420982 ENSP00000409004
ENST00000421070 ENSP00000388003
ENST00000495365
ENST00000492577
ENST00000472213
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
Experimentally validated
Total 8 [view]
Protein-Protein 7 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0016787 hydrolase activity
Biological Process
GO:0006631 fatty acid metabolic process
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000028670
View Gene Order
Pathways
NETPATH
REACTOME
KEGG
hsa00564
Glycerophospholipid metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL Q5QPN5 Q5QPQ3
UniProt Splice Variant
Entrez Gene 11313
UniGene Hs.533479 Hs.730360
RefSeq NM_007260
HUGO HGNC:6738
OMIM
CCDS CCDS241
HPRD 07127
IMGT
EMBL AL031295
GenPept
RNA Seq Atlas 11313

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca