Version 5.4
Homo sapiens Gene: GJA10
Summary
InnateDB Gene IDBG-94350.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GJA10
Gene Name gap junction protein, alpha 10, 62kDa
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000135355
Encoded Proteins
IDBP-94352
gap junction protein, alpha 10, 62kDa
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Connexins, such as GJA10, are involved in the formation of gap junctions, intercellular conduits that directly connect the cytoplasms of contacting cells. Each gap junction channel is formed by docking of 2 hemichannels, each of which contains 6 connexin subunits (Sohl et al., 2003 [PubMed 12881038]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:89894469-89896120
Strand Forward strand
Band q15
Transcripts
ENST00000369352 ENSP00000358358
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0005243 gap junction channel activity
Biological Process
GO:0007268 synaptic transmission
GO:0007276 gamete generation
GO:0007416 synapse assembly
GO:0009416 response to light stimulus
GO:0050908 detection of light stimulus involved in visual perception
GO:0055085 transmembrane transport
Cellular Component
GO:0005886 plasma membrane
GO:0005921 gap junction
GO:0005922 connexon complex
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000051056
View Gene Order
ENSBTAG00000011315
Not yet available
Pathways
NETPATH
REACTOME
REACT_9509
Gap junction assembly pathway
REACT_16970
Electric Transmission Across Gap Junctions pathway
REACT_13685
Neuronal System pathway
REACT_16881
Transmission across Electrical Synapses pathway
REACT_9411
Gap junction trafficking pathway
REACT_9480
Gap junction trafficking and regulation pathway
REACT_11123
Membrane Trafficking pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q969M2
TrEMBL
UniProt Splice Variant
Entrez Gene 84694
UniGene Hs.334499
RefSeq NM_032602
HUGO HGNC:16995
OMIM 611924
CCDS CCDS5025
HPRD 13104
IMGT
EMBL AF296766 AJ414565 AL353692 CH471051
GenPept AAK51676 CAC93847 CAI16242 EAW48537
RNA Seq Atlas 84694

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca