Version 5.4
Homo sapiens Gene: MAN1C1
Summary
InnateDB Gene IDBG-94363.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MAN1C1
Gene Name mannosidase, alpha, class 1C, member 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000117643
Encoded Proteins
IDBP-94367
mannosidase, alpha, class 1C, member 1
IDBP-94371
mannosidase, alpha, class 1C, member 1
IDBP-94373
mannosidase, alpha, class 1C, member 1
IDBP-812070
mannosidase, alpha, class 1C, member 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:25617468-25786207
Strand Forward strand
Band p36.11
Transcripts
ENST00000374332 ENSP00000363452
ENST00000263979 ENSP00000263979
ENST00000374329 ENSP00000363449
ENST00000473891
ENST00000496532
ENST00000475314
ENST00000487493
ENST00000611903 ENSP00000482317
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
GO:0005509 calcium ion binding
Biological Process
GO:0006487 protein N-linked glycosylation
GO:0008152 metabolic process
GO:0018279 protein N-linked glycosylation via asparagine
GO:0043687 post-translational protein modification
GO:0044267 cellular protein metabolic process
Cellular Component
GO:0000139 Golgi membrane
GO:0016020 membrane
GO:0030173 integral component of Golgi membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000037306
View Gene Order
ENSBTAG00000003069
Not yet available
Pathways
NETPATH
REACTOME
REACT_25396
Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2 pathway
REACT_25210
N-glycan trimming and elongation in the cis-Golgi pathway
REACT_25046
Transport to the Golgi and subsequent modification pathway
REACT_22426
Asparagine N-linked glycosylation pathway
REACT_22161
Post-translational protein modification pathway
REACT_17015
Metabolism of proteins pathway
KEGG
hsa00510
N-Glycan biosynthesis pathway
hsa04141
Protein processing in endoplasmic reticulum pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL A6NGN6 B1AJZ5
UniProt Splice Variant
Entrez Gene 57134
UniGene
RefSeq XM_005245945 NM_001289010 NM_020379
HUGO HGNC:19080
OMIM
CCDS CCDS265
HPRD 14354
IMGT
EMBL AL020996 AL031280
GenPept
RNA Seq Atlas 57134

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca