Homo sapiens Gene: FBXL4 | |||||||||||||||||||
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Summary | |||||||||||||||||||
InnateDB Gene | IDBG-94524.6 | ||||||||||||||||||
Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||||||||||||
Gene Symbol | FBXL4 | ||||||||||||||||||
Gene Name | F-box and leucine-rich repeat protein 4 | ||||||||||||||||||
Synonyms | |||||||||||||||||||
Species | Homo sapiens | ||||||||||||||||||
Ensembl Gene | ENSG00000112234 | ||||||||||||||||||
Encoded Proteins |
F-box and leucine-rich repeat protein 4
F-box and leucine-rich repeat protein 4
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Protein Structure |
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Useful resources | Stemformatics EHFPI ImmGen | ||||||||||||||||||
Entrez Gene | |||||||||||||||||||
Summary |
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbls class and, in addition to an F-box, contains at least 9 tandem leucine-rich repeats. [provided by RefSeq, Jul 2008] |
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Gene Information | |||||||||||||||||||
Type | Protein coding | ||||||||||||||||||
Genomic Location | Chromosome 6:98868538-98948006 | ||||||||||||||||||
Strand | Reverse strand | ||||||||||||||||||
Band | q16.2 | ||||||||||||||||||
Transcripts |
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Interactions | |||||||||||||||||||
Number of Interactions |
This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
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Gene Ontology | |||||||||||||||||||
Molecular Function |
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Biological Process |
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Cellular Component |
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Orthologs | |||||||||||||||||||
Species
Mus musculus
Bos taurus
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Gene ID
Gene Order
Not yet available
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Cross-References | |||||||||||||||||||
SwissProt | Q9UKA2 | ||||||||||||||||||
TrEMBL | |||||||||||||||||||
UniProt Splice Variant | |||||||||||||||||||
Entrez Gene | 26235 | ||||||||||||||||||
UniGene | Hs.734936 | ||||||||||||||||||
RefSeq | NM_001278716 NM_012160 XM_006715458 | ||||||||||||||||||
HUGO | HGNC:13601 | ||||||||||||||||||
OMIM | 605654 | ||||||||||||||||||
CCDS | CCDS5041 | ||||||||||||||||||
HPRD | 05738 | ||||||||||||||||||
IMGT | |||||||||||||||||||
EMBL | AF174590 AF176699 AF199355 AK313076 AL022395 BC055010 BC091484 CH471051 | ||||||||||||||||||
GenPept | AAF03699 AAF04511 AAF09247 AAH55010 AAH91484 BAG35902 CAB37981 EAW48489 EAW48490 | ||||||||||||||||||
RNA Seq Atlas | 26235 | ||||||||||||||||||