Version 5.4
Homo sapiens Gene: SH3BGRL3
Summary
InnateDB Gene IDBG-94529.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SH3BGRL3
Gene Name SH3 domain binding glutamic acid-rich protein like 3
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000142669
Encoded Proteins
IDBP-94533
SH3 domain binding glutamic acid-rich protein like 3
IDBP-94535
SH3 domain binding glutamic acid-rich protein like 3
IDBP-809130
SH3 domain binding glutamate-rich protein like 3
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:26279176-26281522
Strand Forward strand
Band p36.11
Transcripts
ENST00000270792 ENSP00000270792
ENST00000319041 ENSP00000363358
ENST00000614679 ENSP00000479107
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005100 Rho GTPase activator activity
GO:0009055 electron carrier activity
GO:0015035 protein disulfide oxidoreductase activity
GO:0030215 semaphorin receptor binding
Biological Process
GO:0030834 regulation of actin filament depolymerization
GO:0032321 positive regulation of Rho GTPase activity
GO:0032956 regulation of actin cytoskeleton organization
GO:0043535 regulation of blood vessel endothelial cell migration
GO:0045454 cell redox homeostasis
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0030027 lamellipodium
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028843
View Gene Order
ENSBTAG00000009580
Not yet available
Cross-References
SwissProt Q9H299
TrEMBL Q5T123
UniProt Splice Variant
Entrez Gene 83442
UniGene Hs.109051
RefSeq NM_031286
HUGO HGNC:15568
OMIM 615679
CCDS CCDS278
HPRD
IMGT
EMBL AF247790 AF304163 AJ297915 AL451139 BC030135
GenPept AAG41412 AAH30135 AAL95695 CAC35770 CAI15827
RNA Seq Atlas 83442

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca