Version 5.4
Homo sapiens Protein: SH3BGRL3
Summary
InnateDB Protein IDBP-809130.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SH3BGRL3
Protein Name SH3 domain binding glutamate-rich protein like 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000479107
InnateDB Gene IDBG-94529 (SH3BGRL3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005100 Rho GTPase activator activity
GO:0009055 electron carrier activity
GO:0015035 protein disulfide oxidoreductase activity
GO:0030215 semaphorin receptor binding
Biological Process
GO:0030834 regulation of actin filament depolymerization
GO:0032321 positive regulation of Rho GTPase activity
GO:0032956 regulation of actin cytoskeleton organization
GO:0043535 regulation of blood vessel endothelial cell migration
GO:0045454 cell redox homeostasis
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0030027 lamellipodium
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR002109 Glutaredoxin
IPR006993 SH3-binding, glutamic acid-rich protein
IPR012336 Thioredoxin-like fold
PFAM PF00462
PF04908
PF13098
PF13192
PF13462
PF13905
PRINTS
PIRSF PIRSF008142
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 83442
UniGene
RefSeq
HUGO HGNC:15568
OMIM 615679
CCDS
HPRD
IMGT
EMBL AF247790 AF304163 AJ297915 AL451139 BC030135
GenPept AAG41412 AAH30135 AAL95695 CAC35770 CAI15827

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca