Version 5.4
Homo sapiens Gene: BVES
Summary
InnateDB Gene IDBG-94774.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol BVES
Gene Name blood vessel epicardial substance
Synonyms HBVES; POP1; POPDC1
Species Homo sapiens
Ensembl Gene ENSG00000112276
Encoded Proteins
IDBP-94776
blood vessel epicardial substance
IDBP-94778
blood vessel epicardial substance
IDBP-385662
blood vessel epicardial substance
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene encodes a member of the POP family of proteins containing three putative transmembrane domains. This gene is expressed in cardiac and skeletal muscle and may play an important role in development of these tissues. The mouse ortholog may be involved in the regeneration of adult skeletal muscle and may act as a cell adhesion molecule in coronary vasculogenesis. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:105096822-105137174
Strand Reverse strand
Band q21
Transcripts
ENST00000336775 ENSP00000337259
ENST00000314641 ENSP00000313172
ENST00000446408 ENSP00000397310
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
GO:0005515 protein binding
GO:0030552 cAMP binding
Biological Process
GO:0001921 positive regulation of receptor recycling
GO:0002027 regulation of heart rate
GO:0002244 hematopoietic progenitor cell differentiation
GO:0007517 muscle organ development
GO:0008360 regulation of cell shape
GO:0016192 vesicle-mediated transport
GO:0032314 regulation of Rac GTPase activity
GO:0034446 substrate adhesion-dependent cell spreading
GO:0040017 positive regulation of locomotion
GO:0042391 regulation of membrane potential
GO:0043088 regulation of Cdc42 GTPase activity
GO:0060931 sinoatrial node cell development
GO:0090136 epithelial cell-cell adhesion
Cellular Component
GO:0005886 plasma membrane
GO:0005923 tight junction
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016328 lateral plasma membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000071317
View Gene Order
ENSBTAG00000018790
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.221660 Hs.736835
RefSeq NM_001199563 NM_007073 NM_147147
HUGO
OMIM
CCDS CCDS5051
HPRD 06842
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca