Version 5.4
Homo sapiens Gene: REV3L
Summary
InnateDB Gene IDBG-95364.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol REV3L
Gene Name REV3-like, polymerase (DNA directed), zeta, catalytic subunit
Synonyms POLZ; REV3
Species Homo sapiens
Ensembl Gene ENSG00000009413
Encoded Proteins
IDBP-95370
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
IDBP-95372
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
IDBP-95374
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
IDBP-386146
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
IDBP-386149
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
IDBP-386150
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
IDBP-386151
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
IDBP-810674
REV3-like, polymerase (DNA directed), zeta, catalytic subunit
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:111299028-111483715
Strand Reverse strand
Band q21
Transcripts
ENST00000368805 ENSP00000357795
ENST00000368802 ENSP00000357792
ENST00000358835 ENSP00000351697
ENST00000422377 ENSP00000393184
ENST00000434009 ENSP00000391605
ENST00000435970 ENSP00000402003
ENST00000413831 ENSP00000400600
ENST00000462119
ENST00000492520
ENST00000467500
ENST00000470871
ENST00000460981
ENST00000494858
ENST00000619481 ENSP00000482892
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0003887 DNA-directed DNA polymerase activity
GO:0005515 protein binding
GO:0046872 metal ion binding
GO:0051539 4 iron, 4 sulfur cluster binding
Biological Process
GO:0006139 nucleobase-containing compound metabolic process
GO:0006260 DNA replication
GO:0006261 DNA-dependent DNA replication
GO:0006281 DNA repair
GO:0019985 translesion synthesis
Cellular Component
GO:0005634 nucleus
GO:0005694 chromosome
GO:0016035 zeta DNA polymerase complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000019841
View Gene Order
ENSBTAG00000010760
Not yet available
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.232021
RefSeq NM_001286431 NM_001286432 NM_002912 XM_005267090 XM_005267091 XM_006715543 XM_006715544
HUGO
OMIM
CCDS CCDS5091 CCDS69177
HPRD 04145
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca