Version 5.4
Homo sapiens Gene: TINAGL1
Summary
InnateDB Gene IDBG-95453.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TINAGL1
Gene Name tubulointerstitial nephritis antigen-like 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000142910
Encoded Proteins
IDBP-95457
tubulointerstitial nephritis antigen-like 1
IDBP-378192
tubulointerstitial nephritis antigen-like 1
IDBP-600137
tubulointerstitial nephritis antigen-like 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The protein encoded by this gene is similar in sequence to tubulointerstitial nephritis antigen, a secreted glycoprotein that is recognized by antibodies in some types of immune-related tubulointerstitial nephritis. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:31576485-31587686
Strand Forward strand
Band p35.2
Transcripts
ENST00000271064 ENSP00000271064
ENST00000457433 ENSP00000395137
ENST00000461030
ENST00000466998
ENST00000478398
ENST00000481165
ENST00000468635
ENST00000498429
ENST00000463112
ENST00000480586
ENST00000537531 ENSP00000445392
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 11 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005044 scavenger receptor activity
GO:0005201 extracellular matrix structural constituent
GO:0008234 cysteine-type peptidase activity
GO:0030247 polysaccharide binding
GO:0043236 laminin binding
Biological Process
GO:0006508 proteolysis
GO:0006898 receptor-mediated endocytosis
GO:0006955 immune response
GO:0016197 endosomal transport
Cellular Component
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0031012 extracellular matrix
GO:0070062 extracellular vesicular exosome
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028776
View Gene Order
ENSBTAG00000013235
Not yet available
Cross-References
SwissProt Q9GZM7
TrEMBL B4DVG5
UniProt Splice Variant
Entrez Gene 64129
UniGene
RefSeq NM_022164 NM_001204414 NM_001204415 XM_005271107
HUGO HGNC:19168
OMIM
CCDS CCDS343 CCDS55586 CCDS72745
HPRD 07122
IMGT
EMBL AB050716 AB050719 AC114488 AF205436 AF236150 AF236151 AF236152 AF236153 AF236154 AF236155 AF289569 AK027839 AK074124 AK075398 AK292770 AK298382 AK301070 AY358421 BC009048 BC064633 CH471059
GenPept AAG33699 AAG38876 AAG40154 AAH09048 AAH64633 AAL55753 AAQ88787 BAB18636 BAB18727 BAB55403 BAB84950 BAC11596 BAF85459 BAG60618 BAG62677 EAX07604 EAX07605 EAX07606
RNA Seq Atlas 64129

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca