Version 5.4
Homo sapiens Gene: GPRC6A
Summary
InnateDB Gene IDBG-95756.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPRC6A
Gene Name G protein-coupled receptor, family C, group 6, member A
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000173612
Encoded Proteins
IDBP-95758
G protein-coupled receptor, family C, group 6, member A
IDBP-95760
G protein-coupled receptor, family C, group 6, member A
IDBP-602584
G protein-coupled receptor, family C, group 6, member A
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Members of family C of the G protein-coupled receptor (GPCR) superfamily, such as GPRC6A, are characterized by an evolutionarily conserved amino acid-sensing motif linked to an intramembranous 7-transmembrane loop region. Several members of GPCR family C, including GPRC6A, also have a long N-terminal domain (summary by Pi et al., 2005 [PubMed 16199532]).[supplied by OMIM, Nov 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:116792085-116829037
Strand Reverse strand
Band q22.1
Transcripts
ENST00000310357 ENSP00000309493
ENST00000368549 ENSP00000357537
ENST00000530250 ENSP00000433465
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004930 G-protein coupled receptor activity
Biological Process
GO:0007186 G-protein coupled receptor signaling pathway
GO:0019722 calcium-mediated signaling
GO:0043200 response to amino acid
Cellular Component
GO:0005886 plasma membrane
GO:0009986 cell surface
GO:0016021 integral component of membrane
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000019905
View Gene Order
Pathways
NETPATH
REACTOME
REACT_18283
G alpha (q) signalling events pathway
REACT_120966
Gastrin-CREB signalling pathway via PKC and MAPK pathway
REACT_18319
Class C/3 (Metabotropic glutamate/pheromone receptors) pathway
REACT_14797
Signaling by GPCR pathway
REACT_111102
Signal Transduction pathway
REACT_19184
GPCR downstream signaling pathway
REACT_21340
GPCR ligand binding pathway
KEGG
INOH
PID NCI
Cross-References
SwissProt Q5T6X5
TrEMBL
UniProt Splice Variant
Entrez Gene 222545
UniGene Hs.266745
RefSeq NM_001286355 NM_001286354 NM_148963
HUGO HGNC:18510
OMIM 613572
CCDS CCDS69184 CCDS5112 CCDS69185
HPRD 17074
IMGT
EMBL AB065680 AB083615 AF502962 AL354716 AY435125 AY435126 AY435127
GenPept AAM22230 AAS13465 AAS13466 AAS13467 BAB89328 BAC05904 CAI16922
RNA Seq Atlas 222545

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca