Version 5.4
Homo sapiens Gene: ADC
Summary
InnateDB Gene IDBG-95872.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ADC
Gene Name arginine decarboxylase
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000142920
Encoded Proteins
IDBP-95874
arginine decarboxylase
IDBP-95876
arginine decarboxylase
IDBP-95880
arginine decarboxylase
IDBP-95882
arginine decarboxylase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 1:33081104-33120530
Strand Forward strand
Band p35.1
Transcripts
ENST00000294517 ENSP00000294517
ENST00000373443 ENSP00000362542
ENST00000373441 ENSP00000362540
ENST00000373440 ENSP00000362539
ENST00000478635
ENST00000481886
ENST00000475935
ENST00000471119
ENST00000462920
ENST00000495135
ENST00000477570
ENST00000483027
ENST00000492420
ENST00000497710
ENST00000473089
ENST00000484656
ENST00000478204
ENST00000497280
ENST00000492521
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
GO:0005515 protein binding
GO:0008792 arginine decarboxylase activity
GO:0015489 putrescine transmembrane transporter activity
GO:0042978 ornithine decarboxylase activator activity
Biological Process
GO:0006591 ornithine metabolic process
GO:0006595 polyamine metabolic process
GO:0006596 polyamine biosynthetic process
GO:0007283 spermatogenesis
GO:0015847 putrescine transport
GO:0034641 cellular nitrogen compound metabolic process
GO:0042177 negative regulation of protein catabolic process
GO:0043085 positive regulation of catalytic activity
GO:0044281 small molecule metabolic process
GO:0097055 agmatine biosynthetic process
GO:1902269 positive regulation of polyamine transmembrane transport
Cellular Component
GO:0005634 nucleus
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:1990005 granular vesicle
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000028789
View Gene Order
ENSBTAG00000020548
Not yet available
Pathways
NETPATH
REACTOME
REACT_14800
Agmatine biosynthesis pathway
REACT_14820
Metabolism of polyamines pathway
REACT_13
Metabolism of amino acids and derivatives pathway
REACT_111217
Metabolism pathway
KEGG
hsa00330
Arginine and proline metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.101807
RefSeq NM_001293562 NM_052998 XM_005270404 XM_006710310
HUGO
OMIM
CCDS CCDS375
HPRD 17657
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca