InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ADC

Summary

InnateDB Protein

IDBP-95874.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ADC

Protein Name

arginine decarboxylase

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000294517

InnateDB Gene

IDBG-95872 (ADC)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003824	catalytic activity
GO:0005515	protein binding
GO:0008792	arginine decarboxylase activity
GO:0015489	putrescine transmembrane transporter activity
GO:0042978	ornithine decarboxylase activator activity

Biological Process

GO:0006591	ornithine metabolic process
GO:0006595	polyamine metabolic process
GO:0006596	polyamine biosynthetic process
GO:0007283	spermatogenesis
GO:0015847	putrescine transport
GO:0034641	cellular nitrogen compound metabolic process
GO:0042177	negative regulation of protein catabolic process
GO:0043085	positive regulation of catalytic activity
GO:0044281	small molecule metabolic process
GO:0097055	agmatine biosynthetic process
GO:1902269	positive regulation of polyamine transmembrane transport

Cellular Component

GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005829	cytosol
GO:1990005	granular vesicle

Protein Structure and Domains

PDB ID

InterPro

IPR000183 Ornithine/DAP/Arg decarboxylase
IPR002433 Ornithine decarboxylase
IPR009006 Alanine racemase/group IV decarboxylase, C-terminal
IPR022643 Orn/DAP/Arg decarboxylase 2, C-terminal
IPR022644 Orn/DAP/Arg decarboxylase 2, N-terminal
IPR029066 PLP-binding barrel

PFAM

PF00278
PF02784

PRINTS

PR01179
PR01182

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q96A70