Version 5.4
Homo sapiens Gene: DNALI1
Summary
InnateDB Gene IDBG-96438.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DNALI1
Gene Name dynein, axonemal, light intermediate chain 1
Synonyms dJ423B22.5; hp28; P28
Species Homo sapiens
Ensembl Gene ENSG00000163879
Encoded Proteins
IDBP-96440
dynein, axonemal, light intermediate chain 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects. [provided by RefSeq, Jul 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:37556919-37566857
Strand Forward strand
Band p34.3
Transcripts
ENST00000296218 ENSP00000296218
ENST00000490312
ENST00000466723
ENST00000497858
ENST00000467277
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 12 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003777 microtubule motor activity
GO:0005515 protein binding
GO:0045504 dynein heavy chain binding
Biological Process
GO:0006928 cellular component movement
GO:0007338 single fertilization
GO:0008152 metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005858 axonemal dynein complex
GO:0005930 axoneme
GO:0030175 filopodium
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000042707
View Gene Order
ENSBTAG00000002583
Not yet available
Pathways
NETPATH
REACTOME
KEGG
hsa05016
Huntington's disease pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.406050
RefSeq NM_003462
HUGO
OMIM
CCDS CCDS420
HPRD 03681
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca