Version 5.4
Homo sapiens Gene: NT5C1A
Summary
InnateDB Gene IDBG-96740.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol NT5C1A
Gene Name 5'-nucleotidase, cytosolic IA
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000116981
Encoded Proteins
IDBP-96742
5'-nucleotidase, cytosolic IA
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Cytosolic nucleotidases, such as NT5C1A, dephosphorylate nucleoside monophosphates (Hunsucker et al., 2001 [PubMed 11133996]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:39659121-39672038
Strand Reverse strand
Band p34.2
Transcripts
ENST00000235628 ENSP00000235628
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000166 nucleotide binding
GO:0000287 magnesium ion binding
GO:0008253 5'-nucleotidase activity
Biological Process
GO:0006144 purine nucleobase metabolic process
GO:0006195 purine nucleotide catabolic process
GO:0006206 pyrimidine nucleobase metabolic process
GO:0009116 nucleoside metabolic process
GO:0009117 nucleotide metabolic process
GO:0009128 purine nucleoside monophosphate catabolic process
GO:0016311 dephosphorylation
GO:0044281 small molecule metabolic process
GO:0046085 adenosine metabolic process
GO:0046135 pyrimidine nucleoside catabolic process
GO:0055086 nucleobase-containing small molecule metabolic process
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000054958
View Gene Order
ENSBTAG00000002983
Not yet available
Pathways
NETPATH
REACTOME
REACT_1023
Pyrimidine catabolism pathway
REACT_2086
Purine catabolism pathway
REACT_1698
Metabolism of nucleotides pathway
REACT_522
Purine metabolism pathway
REACT_957
Pyrimidine metabolism pathway
REACT_111217
Metabolism pathway
KEGG
hsa00240
Pyrimidine metabolism pathway
hsa00760
Nicotinate and nicotinamide metabolism pathway
hsa00230
Purine metabolism pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.307006
RefSeq NM_032526
HUGO
OMIM
CCDS CCDS440
HPRD 14844
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca