Version 5.4
Homo sapiens Gene: OXCT2
Summary
InnateDB Gene IDBG-96770.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol OXCT2
Gene Name 3-oxoacid CoA transferase 2
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000198754
Encoded Proteins
IDBP-96772
3-oxoacid CoA transferase 2
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary OXCT2 is a testis-specific succinyl-CoA:3-oxoacid CoA transferase (EC 2.8.3.5), which catalyzes the reversible transfer of CoA from succinyl-CoA to acetoacetate in the first step of ketone body utilization. See also OXCT1 (MIM 601424).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:39769523-39771348
Strand Reverse strand
Band p34.2
Transcripts
ENST00000327582 ENSP00000361914
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0008260 3-oxoacid CoA-transferase activity
GO:0008410 CoA-transferase activity
Biological Process
GO:0008152 metabolic process
GO:0046952 ketone body catabolic process
Cellular Component
GO:0005739 mitochondrion
GO:0031514 motile cilium
Orthologs
Species
Mus musculus
Gene ID
Gene Order
ENSMUSG00000076436
View Gene Order
Pathways
NETPATH
REACTOME
KEGG
hsa00280
Valine, leucine and isoleucine degradation pathway
hsa00650
Butanoate metabolism pathway
hsa00072
Synthesis and degradation of ketone bodies pathway
INOH
PID NCI
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene
RefSeq NM_022120
HUGO
OMIM
CCDS CCDS445
HPRD 15093
IMGT
EMBL
GenPept
RNA Seq Atlas

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca