Version 5.4
Homo sapiens Gene: SHPRH
Summary
InnateDB Gene IDBG-97569.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SHPRH
Gene Name SNF2 histone linker PHD RING helicase, E3 ubiquitin protein ligase
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000146414
Encoded Proteins
IDBP-97573
SNF2 histone linker PHD RING helicase
IDBP-97575
SNF2 histone linker PHD RING helicase
IDBP-97577
SNF2 histone linker PHD RING helicase
IDBP-387684
SNF2 histone linker PHD RING helicase
IDBP-387689
SNF2 histone linker PHD RING helicase
IDBP-387693
SNF2 histone linker PHD RING helicase
IDBP-479295
SNF2 histone linker PHD RING helicase
IDBP-481484
SNF2 histone linker PHD RING helicase
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary SHPRH is a ubiquitously expressed protein that contains motifs characteristics of several DNA repair proteins, transcription factors, and helicases. SHPRH is a functional homolog of S. cerevisiae RAD5 (Unk et al., 2006 [PubMed 17108083]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:145864245-145964423
Strand Reverse strand
Band q24.3
Transcripts
ENST00000367505 ENSP00000356475
ENST00000367503 ENSP00000356473
ENST00000275233 ENSP00000275233
ENST00000417762 ENSP00000403790
ENST00000438092 ENSP00000412797
ENST00000433355 ENSP00000408019
ENST00000519632 ENSP00000430528
ENST00000523276
ENST00000520752
ENST00000521977 ENSP00000429548
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 15 experimentally validated interaction(s) in this database.
Experimentally validated
Total 15 [view]
Protein-Protein 15 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004386 helicase activity
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008270 zinc ion binding
GO:0016874 ligase activity
Biological Process
GO:0000209 protein polyubiquitination
GO:0006281 DNA repair
GO:0006334 nucleosome assembly
GO:0008152 metabolic process
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000090112
View Gene Order
ENSBTAG00000008112
Not yet available
Cross-References
SwissProt Q149N8
TrEMBL H7C2W2 Q5JT88
UniProt Splice Variant
Entrez Gene 257218
UniGene Hs.631178 Hs.693012 Hs.723297
RefSeq NM_001042683 NM_173082 XM_006715439 XM_006715440 XM_006715441 XM_006715442 XM_006715443
HUGO HGNC:19336
OMIM 608048
CCDS CCDS43513 CCDS47496
HPRD
IMGT
EMBL AB095943 AK075318 AK094944 AL356599 AL451145 AY161136 AY163808 BC113089 BC117685 BC117686 CR749290
GenPept AAI13090 AAI17686 AAI17687 AAO06907 AAO26201 BAC04459 BAC11544 BAC23119 CAH18145 CAH70765 CAI41120
RNA Seq Atlas 257218

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca