Version 5.4
Homo sapiens Gene: SASH1
Summary
InnateDB Gene IDBG-97665.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SASH1
Gene Name SAM and SH3 domain containing 1
Synonyms dJ323M4; dJ323M4.1; SH3D6A
Species Homo sapiens
Ensembl Gene ENSG00000111961
Encoded Proteins
IDBP-97667
SAM and SH3 domain containing 1
IDBP-97669
SAM and SH3 domain containing 1
IDBP-813837
SAM and SH3 domain containing 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary Currently no Entrez Summary Available. You might want to check the Summary Sections of the Orthologs.
Gene Information
Type Protein coding
Genomic Location Chromosome 6:148272304-148552050
Strand Forward strand
Band q24.3
Transcripts
ENST00000367469 ENSP00000356439
ENST00000367467 ENSP00000356437
ENST00000470750
ENST00000622663 ENSP00000479998
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.
Experimentally validated
Total 17 [view]
Protein-Protein 17 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008022 protein C-terminus binding
GO:0019901 protein kinase binding
GO:0031435 mitogen-activated protein kinase kinase kinase binding
GO:0032947 protein complex scaffold
Biological Process
GO:0000209 protein polyubiquitination
GO:0010595 positive regulation of endothelial cell migration
GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway
GO:0043507 positive regulation of JUN kinase activity
GO:0045766 positive regulation of angiogenesis
GO:1900044 regulation of protein K63-linked ubiquitination
GO:1900745 positive regulation of p38MAPK cascade
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:1902498 regulation of protein autoubiquitination
Cellular Component
GO:0016020 membrane
GO:0043234 protein complex
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000015305
View Gene Order
ENSBTAG00000001826
Not yet available
Cross-References
SwissProt O94885
TrEMBL Q5TGN6
UniProt Splice Variant
Entrez Gene 23328
UniGene Hs.193133 Hs.608017
RefSeq NM_015278 XM_005266874 XM_005266875 XM_006715406
HUGO HGNC:19182
OMIM 607955
CCDS CCDS5212
HPRD
IMGT
EMBL AB018333 AJ507735 AK024403 AL033378 AL357567 AL513164 AL589940 AY351960 AY351961 AY351962 AY351963 AY351964 AY351965 AY351966 AY351967 AY351968 AY351969 AY351970 AY351971 AY351972 AY351973 AY351974 AY351975 AY351976 AY351977 AY351978 AY351979 BC028303 BN000088 CH471051
GenPept AAH28303 AAQ55463 BAA34510 BAB14909 CAD47811 CAD92036 CAH73449 CAI20166 EAW47815
RNA Seq Atlas 23328

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca