Version 5.4
| Homo sapiens Gene: RAET1E | |||||||||
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| Summary | |||||||||
| InnateDB Gene | IDBG-97825.6 | ||||||||
| Last Modified | 2014-10-13 [Report errors or provide feedback] | ||||||||
| Gene Symbol | RAET1E | ||||||||
| Gene Name | retinoic acid early transcript 1E | ||||||||
| Synonyms | |||||||||
| Species | Homo sapiens | ||||||||
| Ensembl Gene | ENSG00000164520 | ||||||||
| Encoded Proteins |
retinoic acid early transcript 1E
retinoic acid early transcript 1E
retinoic acid early transcript 1E
retinoic acid early transcript 1E
retinoic acid early transcript 1E
retinoic acid early transcript 1E
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| Protein Structure |
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| Useful resources | Stemformatics EHFPI ImmGen | ||||||||
| Entrez Gene | |||||||||
| Summary |
This gene belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. This and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011] |
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| Gene Information | |||||||||
| Type | Protein coding | ||||||||
| Genomic Location | Chromosome 6:149883375-149898102 | ||||||||
| Strand | Reverse strand | ||||||||
| Band | q25.1 | ||||||||
| Transcripts | |||||||||
| Interactions | |||||||||
| Number of Interactions |
This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
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| Gene Ontology | |||||||||
Molecular Function |
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| Biological Process |
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| Cellular Component |
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| Orthologs | |||||||||
| No orthologs found for this gene | |||||||||
| Pathways | |||||||||
| NETPATH | |||||||||
| REACTOME |
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell pathway
Adaptive Immune System pathway
Immune System pathway
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| KEGG |
Natural killer cell mediated cytotoxicity pathway
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| INOH | |||||||||
| PID NCI | |||||||||
| Cross-References | |||||||||
| SwissProt | Q8TD07 | ||||||||
| TrEMBL | E9PKJ6 I2GUA6 Q3T1D4 | ||||||||
| UniProt Splice Variant | |||||||||
| Entrez Gene | 135250 | ||||||||
| UniGene | Hs.511818 | ||||||||
| RefSeq | NM_001243325 NM_001243327 NM_001243328 NM_139165 | ||||||||
| HUGO | HGNC:16793 | ||||||||
| OMIM | 609243 | ||||||||
| CCDS | CCDS5221 CCDS59042 CCDS59043 CCDS59044 | ||||||||
| HPRD | |||||||||
| IMGT | |||||||||
| EMBL | AF359243 AL355312 AY054974 AY069961 AY176317 AY252119 AY359075 BC101976 EF489426 HE806192 JX051316 | ||||||||
| GenPept | AAI01977 AAL11005 AAL58090 AAL76417 AAO22240 AAP15166 AAQ89434 ABR29881 AFP19435 CAH72868 CAH72869 CCH57707 | ||||||||
| RNA Seq Atlas | 135250 | ||||||||