Homo sapiens Gene: PPP1R14C
Summary
InnateDB Gene IDBG-97872.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP1R14C
Gene Name protein phosphatase 1, regulatory (inhibitor) subunit 14C
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000198729
Encoded Proteins
protein phosphatase 1, regulatory (inhibitor) subunit 14C
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary The degree of protein phosphorylation is regulated by a balance of protein kinase and phosphatase activities. Protein phosphatase-1 (PP1; see MIM 176875) is a signal-transducing phosphatase that influences neuronal activity, protein synthesis, metabolism, muscle contraction, and cell division. PPP1R14C is an inhibitor of PP1 (Liu et al., 2002 [PubMed 11812771]).[supplied by OMIM, Feb 2010]
Gene Information
Type Protein coding
Genomic Location Chromosome 6:150143076-150250357
Strand Forward strand
Band q25.1
Transcripts
ENST00000361131 ENSP00000355260
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 3 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004865 protein serine/threonine phosphatase inhibitor activity
Biological Process
GO:0042325 regulation of phosphorylation
GO:0043086 negative regulation of catalytic activity
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
Not yet available
Pathways
NETPATH
REACTOME
KEGG
INOH
PID NCI
Integrin-linked kinase signaling
Cross-References
SwissProt
TrEMBL
UniProt Splice Variant
Entrez Gene
UniGene Hs.486798 Hs.595038 Hs.715251
RefSeq NM_030949 XM_005267152
HUGO
OMIM
CCDS CCDS5226
HPRD 17890
IMGT
EMBL
GenPept
RNA Seq Atlas