Version 5.4
Homo sapiens Gene: GLIS1
Summary
InnateDB Gene IDBG-98757.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GLIS1
Gene Name GLIS family zinc finger 1
Synonyms
Species Homo sapiens
Ensembl Gene ENSG00000174332
Encoded Proteins
IDBP-98759
GLIS family zinc finger 1
Protein Structure
Useful resources Stemformatics EHFPI ImmGen
Entrez Gene
Summary GLIS1 is a GLI (MIM 165220)-related Kruppel-like zinc finger protein that functions as an activator and repressor of transcription (Kim et al., 2002 [PubMed 12042312]).[supplied by OMIM, Mar 2008]
Gene Information
Type Protein coding
Genomic Location Chromosome 1:53506237-53734204
Strand Reverse strand
Band p32.3
Transcripts
ENST00000312233 ENSP00000309653
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001227 RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription
GO:0001228 RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 DNA binding
GO:0046872 metal ion binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006357 regulation of transcription from RNA polymerase II promoter
GO:0006366 transcription from RNA polymerase II promoter
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
Cellular Component
GO:0005634 nucleus
Orthologs
Species
Mus musculus
Bos taurus
Gene ID
Gene Order
ENSMUSG00000034762
View Gene Order
ENSBTAG00000017986
Not yet available
Cross-References
SwissProt Q8NBF1
TrEMBL
UniProt Splice Variant
Entrez Gene 148979
UniGene Hs.306691
RefSeq NM_147193 XM_005270505
HUGO HGNC:29525
OMIM 610378
CCDS CCDS582
HPRD
IMGT
EMBL AC105280 AK090634 AK093474 AL591720 BC101799 BC104911 CH471059
GenPept AAI01800 AAI04912 BAC03494 BAC04178 CAH72026 EAX06734
RNA Seq Atlas 148979

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca