Homo sapiens Protein: MTF2
Summary
InnateDB Protein IDBP-100304.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol MTF2
Protein Name metal response element binding transcription factor 2
Synonyms dJ976O13.2; M96; PCL2; TDRD19A;
Species Homo sapiens
Ensembl Protein ENSP00000359326
InnateDB Gene IDBG-100300 (MTF2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 21 experimentally validated interaction(s) in this database.
They are also associated with 15 interaction(s) predicted by orthology.
Experimentally validated
Total 21 [view]
Protein-Protein 19 [view]
Protein-DNA 2 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 15 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0008270 zinc ion binding
GO:0035064 methylated histone binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0007379 segment specification
GO:0016568 chromatin modification
GO:0019827 stem cell maintenance
GO:0045944 positive regulation of transcription from RNA polymerase II promoter
GO:0048863 stem cell differentiation
GO:0061086 negative regulation of histone H3-K27 methylation
GO:0061087 positive regulation of histone H3-K27 methylation
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0035098 ESC/E(Z) complex
Protein Structure and Domains
PDB ID
InterPro IPR001965 Zinc finger, PHD-type
IPR002999 Tudor domain
IPR011011 Zinc finger, FYVE/PHD-type
IPR019787 Zinc finger, PHD-finger
PFAM PF00567
PF00628
PRINTS
PIRSF
SMART SM00249
SM00333
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y483
PhosphoSite PhosphoSite-Q9Y483
TrEMBL Q96G26
UniProt Splice Variant
Entrez Gene 22823
UniGene Hs.743474
RefSeq NP_001157864
HUGO HGNC:29535
OMIM 609882
CCDS CCDS53340
HPRD 14342
IMGT
EMBL AC093577 AF072814 AF073293 AJ010014 AK290318 AL117354 BC010013
GenPept AAC27080 AAC27618 AAH10013 BAF83007 CAA08970 CAI23502