InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SYCP1

Summary

InnateDB Protein

IDBP-101330.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SYCP1

Protein Name

synaptonemal complex protein 1

Synonyms

CT8; HOM-TES-14; SCP-1; SCP1;

Species

Homo sapiens

Ensembl Protein

ENSP00000358535

InnateDB Gene

IDBG-101328 (SYCP1)

Protein Structure

UniProt Annotation

Function

Major component of the transverse filaments of synaptonemal complexes (SCS), formed between homologous chromosomes during meiotic prophase.

Subcellular Localization

Nucleus {ECO:0000250}. Chromosome {ECO:0000250}. Note=In tripartite segments of synaptonemal complexes, between lateral elements in the nucleus. Found only where the chromosome cores are synapsed. Its N-terminus is found towards the center of the synaptonemal complex while the C- terminus extends well into the lateral domain of the synaptonemal complex (By similarity). {ECO:0000250}.

Disease Associations

Tissue Specificity

Testis.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0005515	protein binding

Biological Process

GO:0000711	meiotic DNA repair synthesis
GO:0007130	synaptonemal complex assembly
GO:0007131	reciprocal meiotic recombination
GO:0007283	spermatogenesis
GO:0032880	regulation of protein localization
GO:0035092	sperm chromatin condensation
GO:0051026	chiasma assembly
GO:0051878	lateral element assembly