Homo sapiens Protein: VPS72
Summary
InnateDB Protein IDBP-102318.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VPS72
Protein Name vacuolar protein sorting 72 homolog (S. cerevisiae)
Synonyms CFL1; Swc2; TCFL1; YL-1; YL1;
Species Homo sapiens
Ensembl Protein ENSP00000357887
InnateDB Gene IDBG-102316 (VPS72)
Protein Structure
UniProt Annotation
Function Could be a DNA-binding transcriptional regulator. May be involved in chromatin modification and remodeling.
Subcellular Localization Nucleus.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 23 [view]
Protein-Protein 21 [view]
Protein-DNA 1 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006325 chromatin organization
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0016568 chromatin modification
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0043234 protein complex
Protein Structure and Domains
PDB ID
InterPro IPR008895 YL1 nuclear
IPR013272 YL1 nuclear, C-terminal
PFAM PF05764
PF08265
PRINTS
PIRSF
SMART SM00993
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q15906
PhosphoSite PhosphoSite-Q15906
TrEMBL
UniProt Splice Variant
Entrez Gene 6944
UniGene
RefSeq NP_005988
HUGO HGNC:11644
OMIM 600607
CCDS CCDS989
HPRD 02791
IMGT
EMBL AK222935 AK222939 AL592424 BC003151 BT019356 BT019357 CH471121 CX163016 D43642
GenPept AAH03151 AAV38163 AAV38164 BAA07757 BAD96655 BAD96659 CAI16385 EAW53462