Version 5.4
Homo sapiens Protein: VPS72
Summary
InnateDB Protein IDBP-102320.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol VPS72
Protein Name vacuolar protein sorting 72 homolog (S. cerevisiae)
Synonyms CFL1; Swc2; TCFL1; YL-1; YL1;
Species Homo sapiens
Ensembl Protein ENSP00000346464
InnateDB Gene IDBG-102316 (VPS72)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 23 [view]
Protein-Protein 21 [view]
Protein-DNA 1 [view]
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0005515 protein binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0006325 chromatin organization
GO:0006351 transcription, DNA-templated
GO:0006355 regulation of transcription, DNA-templated
GO:0016568 chromatin modification
GO:0035019 somatic stem cell maintenance
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0043234 protein complex
Protein Structure and Domains
PDB ID
InterPro IPR008895 YL1 nuclear
IPR013272 YL1 nuclear, C-terminal
PFAM PF05764
PF08265
PRINTS
PIRSF
SMART SM00993
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q15906
PhosphoSite PhosphoSite-Q15906
TrEMBL
UniProt Splice Variant
Entrez Gene 6944
UniGene
RefSeq NP_001258016
HUGO HGNC:11644
OMIM 600607
CCDS CCDS59201
HPRD 02791
IMGT
EMBL AK222935 AK222939 AL592424 BC003151 BT019356 BT019357 CH471121 CX163016 D43642
GenPept AAH03151 AAV38163 AAV38164 BAA07757 BAD96655 BAD96659 CAI16385 EAW53462

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca