InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: S100A10

Summary

InnateDB Protein

IDBP-102456.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

S100A10

Protein Name

S100 calcium binding protein A10

Synonyms

42C; ANX2L; ANX2LG; Ca[1]; CAL1L; CLP11; GP11; p10; P11;

Species

Homo sapiens

Ensembl Protein

ENSP00000357801

InnateDB Gene

IDBG-102454 (S100A10)

Protein Structure

UniProt Annotation

Function

Because S100A10 induces the dimerization of ANXA2/p36, it may function as a regulator of protein phosphorylation in that the ANXA2 monomer is the preferred target (in vitro) of tyrosine- specific kinase.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	41 [view]
Protein-Protein	41 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0042803	protein homodimerization activity
GO:0044325	ion channel binding

Biological Process

GO:0001765	membrane raft assembly
GO:0006900	membrane budding
GO:0032855	positive regulation of Rac GTPase activity
GO:0045087	innate immune response (InnateDB)
GO:0051099	positive regulation of binding
GO:0051290	protein heterotetramerization
GO:0051496	positive regulation of stress fiber assembly
GO:0051894	positive regulation of focal adhesion assembly
GO:0071229	cellular response to acid
GO:0090002	establishment of protein localization to plasma membrane
GO:1900026	positive regulation of substrate adhesion-dependent cell spreading