InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: S100A4

Summary

InnateDB Protein

IDBP-102701.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

S100A4

Protein Name

S100 calcium binding protein A4

Synonyms

18A2; 42A; CAPL; FSP1; MTS1; P9KA; PEL98;

Species

Homo sapiens

Ensembl Protein

ENSP00000357703

InnateDB Gene

IDBG-102693 (S100A4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Ubiquitously expressed.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 40 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	40 [view]
Protein-Protein	38 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0044822	poly(A) RNA binding
GO:0050786	RAGE receptor binding

Biological Process

GO:0001837	epithelial to mesenchymal transition
GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling

Cellular Component

GO:0005615	extracellular space
GO:0005634	nucleus
GO:0048471	perinuclear region of cytoplasm
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR002048 EF-hand domain
IPR013787 S100/CaBP-9k-type, calcium binding, subdomain

PFAM

PF00036
PF13202
PF13405
PF01023

PRINTS

PIRSF

SMART

SM00054

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P26447

PhosphoSite

PhosphoSite-P26447

TrEMBL

UniProt Splice Variant

Entrez Gene

6275

UniGene

RefSeq

HUGO

HGNC:10494

OMIM

114210

CCDS

CCDS1042

HPRD

15914

IMGT

EMBL

AK292083 BC000838 BC016300 BX470102 CH471121 CR450345 M80563 Z18950 Z33457

GenPept

AAA51920 AAH00838 AAH16300 BAF84772 CAA79474 CAA83880 CAG29341 CAI14754 EAW53310 EAW53311 EAW53312 EAW53313 EAW53314 EAW53315