Version 5.4
Homo sapiens Protein: TPM3
Summary
InnateDB Protein IDBP-102874.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TPM3
Protein Name tropomyosin 3
Synonyms CAPM1; CFTD; HEL-189; HEL-S-82p; hscp30; NEM1; OK/SW-cl.5; TM-5; TM3; TM30; TM30nm; TM5; TPMsk3; TRK;
Species Homo sapiens
Ensembl Protein ENSP00000357520
InnateDB Gene IDBG-102860 (TPM3)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 57 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 57 [view]
Protein-Protein 56 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0003779 actin binding
Biological Process
GO:0006928 cellular component movement
GO:0006936 muscle contraction
GO:0007165 signal transduction
GO:0030049 muscle filament sliding
Cellular Component
GO:0001725 stress fiber
GO:0005829 cytosol
GO:0005856 cytoskeleton
GO:0005862 muscle thin filament tropomyosin
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR000533 Tropomyosin
IPR011072 HR1 rho-binding repeat
PFAM PF00261
PF12718
PF02185
PRINTS PR00194
PIRSF
SMART SM00742
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P06753
PhosphoSite PhosphoSite-P06753
TrEMBL Q6LDX7
UniProt Splice Variant
Entrez Gene 7170
UniGene Hs.715250
RefSeq NP_001265118
HUGO HGNC:12012
OMIM 191030
CCDS CCDS60275
HPRD 01840
IMGT
EMBL AF474157 AL590431 AY004867 BC000771 BC008407 BC008425 BC015403 BC072428 CH471121 DQ120714 M12128 X03541 X04201 X04588
GenPept AAA36775 AAF87083 AAH00771 AAH08407 AAH08425 AAH15403 AAH72428 AAL84570 ABC40673 CAA27243 CAA27798 CAB37185 CAH71264 CAH71269 EAW53229 EAW53230 EAW53231 EAW53235

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca