InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PYGO2

Summary

InnateDB Protein

IDBP-103004.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PYGO2

Protein Name

pygopus homolog 2 (Drosophila)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000357442

InnateDB Gene

IDBG-103002 (PYGO2)

Protein Structure

UniProt Annotation

Function

Involved in signal transduction through the Wnt pathway.

Subcellular Localization

Nucleus {ECO:0000305}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 19 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003682	chromatin binding
GO:0005515	protein binding
GO:0008270	zinc ion binding
GO:0035034	histone acetyltransferase regulator activity
GO:0042393	histone binding

Biological Process

GO:0001701	in utero embryonic development
GO:0001822	kidney development
GO:0002088	lens development in camera-type eye
GO:0007286	spermatid development
GO:0007289	spermatid nucleus differentiation
GO:0007420	brain development
GO:0009791	post-embryonic development
GO:0016055	Wnt signaling pathway
GO:0030879	mammary gland development
GO:0033599	regulation of mammary gland epithelial cell proliferation
GO:0035065	regulation of histone acetylation
GO:0035563	positive regulation of chromatin binding
GO:0048589	developmental growth
GO:0051569	regulation of histone H3-K4 methylation
GO:0060021	palate development
GO:0060070	canonical Wnt signaling pathway