Version 5.4
Homo sapiens Protein: LMNA
Summary
InnateDB Protein IDBP-103396.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LMNA
Protein Name lamin A/C
Synonyms CDCD1; CDDC; CMD1A; CMT2B1; EMD2; FPL; FPLD; FPLD2; HGPS; IDC; LDP1; LFP; LGMD1B; LMN1; LMNC; LMNL1; PRO1;
Species Homo sapiens
Ensembl Protein ENSP00000357280
InnateDB Gene IDBG-103380 (LMNA)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 247 experimentally validated interaction(s) in this database.
They are also associated with 55 interaction(s) predicted by orthology.
Experimentally validated
Total 247 [view]
Protein-Protein 239 [view]
Protein-DNA 8 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 55 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005198 structural molecule activity
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005882 intermediate filament
Protein Structure and Domains
PDB ID
InterPro IPR001322 Lamin Tail Domain
IPR001664 Intermediate filament protein
PFAM PF00932
PF00038
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5TCI8
UniProt Splice Variant
Entrez Gene 4000
UniGene Hs.707716
RefSeq NP_001269553
HUGO HGNC:6636
OMIM 150330
CCDS CCDS72942
HPRD 01035
IMGT
EMBL AK294217 AL135927 AL355388 AL356734
GenPept BAG57524

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca