Version 5.4
Homo sapiens Protein: SH2D2A
Summary
InnateDB Protein IDBP-103631.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SH2D2A
Protein Name SH2 domain containing 2A
Synonyms F2771; SCAP; TSAD; VRAP;
Species Homo sapiens
Ensembl Protein ENSP00000357181
InnateDB Gene IDBG-103627 (SH2D2A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 20 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 20 [view]
Protein-Protein 20 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005070 SH3/SH2 adaptor activity
GO:0005515 protein binding
GO:0017124 SH3 domain binding
Biological Process
GO:0001525 angiogenesis
GO:0007165 signal transduction
GO:0009967 positive regulation of signal transduction
GO:0030154 cell differentiation
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000980 SH2 domain
PFAM PF00017
PF14633
PRINTS PR00401
PIRSF
SMART SM00252
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NP31
PhosphoSite PhosphoSite-Q9NP31
TrEMBL
UniProt Splice Variant
Entrez Gene 9047
UniGene Hs.103527
RefSeq NP_001154915
HUGO HGNC:10821
OMIM 604514
CCDS CCDS53380
HPRD 05152
IMGT
EMBL AF051325 AF097744 AF106072 AJ000553 AK222737 AL158169 AL590666 AY763100 BC012107
GenPept AAC99298 AAF43260 AAF69027 AAH12107 AAV34675 BAD96457 CAA04185 CAH70007 CAH70008 CAI16336 CAI16337

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca