Version 5.4
Homo sapiens Protein: SLAMF8
Summary
InnateDB Protein IDBP-103938.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SLAMF8
Protein Name SLAM family member 8
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000289707
InnateDB Gene IDBG-103936 (SLAMF8)
Protein Structure
UniProt Annotation
Function May play a role in B-lineage commitment and/or modulation of signaling through the B-cell receptor. {ECO:0000269PubMed:11313408}.
Subcellular Localization Membrane; Single-pass type I membrane protein.
Disease Associations
Tissue Specificity Expressed in lymph node, spleen, thymus and bone marrow. {ECO:0000269PubMed:11313408}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
GO:0004872 receptor activity
GO:0005515 protein binding
Biological Process
GO:0033860 regulation of NAD(P)H oxidase activity
GO:0035690 cellular response to drug
GO:0042742 defense response to bacterium
GO:0043549 regulation of kinase activity
GO:0045087 innate immune response (InnateDB)
GO:0090383 phagosome acidification
Cellular Component
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR007110 Immunoglobulin-like domain
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9P0V8
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 56833
UniGene Hs.438683
RefSeq NP_064510
HUGO HGNC:21391
OMIM 606620
CCDS CCDS1188
HPRD 09429
IMGT
EMBL AF146761 AK074669 AL590560 BC109194
GenPept AAF67470 AAI09195 BAC11123 CAH71103 CAH71104

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca