InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: NHLH1

Summary

InnateDB Protein

IDBP-104047.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

NHLH1

Protein Name

nescient helix loop helix 1

Synonyms

bHLHa35; HEN1; NSCL; NSCL1;

Species

Homo sapiens

Ensembl Protein

ENSP00000302189

InnateDB Gene

IDBG-104045 (NHLH1)

Protein Structure

UniProt Annotation

Function

May serve as DNA-binding protein and may be involved in the control of cell-type determination, possibly within the developing nervous system.

Subcellular Localization

Nucleus {ECO:0000255PROSITE- ProRule:PRU00981}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000977	RNA polymerase II regulatory region sequence-specific DNA binding
GO:0001228	RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0046983	protein dimerization activity

Biological Process

GO:0006351	transcription, DNA-templated
GO:0007417	central nervous system development
GO:0030154	cell differentiation
GO:0045944	positive regulation of transcription from RNA polymerase II promoter