InnateDB Protein
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IDBP-104053.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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SLAMF6
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Protein Name
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SLAM family member 6
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000357038
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InnateDB Gene
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IDBG-104051 (SLAMF6)
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Protein Structure
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Function |
Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. {ECO:0000269PubMed:11489943}.
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Subcellular Localization |
Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
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Disease Associations |
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Tissue Specificity |
Expressed by all (resting and activated) natural killer cells (NK), T- and B-lymphocytes. {ECO:0000269PubMed:11489943}.
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated |
Total |
3
[view]
|
Protein-Protein |
3
[view]
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Protein-DNA |
0
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Molecular Function |
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Biological Process |
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Cellular Component |
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PDB ID |
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InterPro |
IPR003599
Immunoglobulin subtype
IPR007110
Immunoglobulin-like domain
IPR013106
Immunoglobulin V-set domain
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PFAM |
PF07686
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PRINTS |
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PIRSF |
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SMART |
SM00409
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TIGRFAMs |
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Modification |
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SwissProt |
Q96DU3
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PhosphoSite |
PhosphoSite-Q96DU3
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TrEMBL |
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UniProt Splice Variant |
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Entrez Gene |
114836
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UniGene |
Hs.492348
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RefSeq |
NP_443163
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HUGO |
HGNC:21392
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OMIM |
606446
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CCDS |
CCDS1205
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HPRD |
05920
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IMGT |
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EMBL |
AJ277141
AJ306388
AK125624
AK301026
AK313549
AL138930
AL832854
AY358159
BC113893
BC114495
CH471121
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GenPept |
AAI13894
AAI14496
AAQ88526
BAG36325
BAG54223
BAG62642
CAC59749
CAC59750
CAI15155
CAI15156
CAI15157
CAI46161
EAW52713
EAW52715
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