Version 5.4
Homo sapiens Protein: FCRLB
Summary
InnateDB Protein IDBP-104346.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FCRLB
Protein Name Fc receptor-like B
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000338598
InnateDB Gene IDBG-104342 (FCRLB)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm. Endoplasmic reticulum. Note=Seems not to be secreted.
Disease Associations
Tissue Specificity Expressed at low levels. Expressed in B- lymphocytes. Detected in tonsil, lung, kidney, spleen and placenta. Expressed by a small subset of germinal center B-cells in tonsils and by melanocytes (at protein level). {ECO:0000269PubMed:15551350, ECO:0000269PubMed:15676285, ECO:0000269PubMed:15815692, ECO:0000269PubMed:16263223}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
Protein Structure and Domains
PDB ID
InterPro IPR003599 Immunoglobulin subtype
IPR007110 Immunoglobulin-like domain
PFAM
PRINTS
PIRSF
SMART SM00409
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q6BAA4
PhosphoSite PhosphoSite-Q6BAA4
TrEMBL
UniProt Splice Variant
Entrez Gene 127943
UniGene Hs.517422
RefSeq NP_001275760
HUGO HGNC:26431
OMIM 609251
CCDS CCDS72962
HPRD 08093
IMGT
EMBL AK290733 AL359541 AY670683 AY670684 AY670685 AY670686 AY670687 AY786314 BC038564 DQ021957 EF064728
GenPept AAH38564 AAT77987 AAT77988 AAT77989 AAT77990 AAT77991 AAX11390 AAY42534 ABK41911 BAF83422 CAH74155 CAM20340 CAM20341 CAM20342 CAM20343

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca