InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: FMO4

Summary

InnateDB Protein

IDBP-104791.4

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

FMO4

Protein Name

flavin containing monooxygenase 4

Synonyms

FMO2;

Species

Homo sapiens

Ensembl Protein

ENSP00000356723

InnateDB Gene

IDBG-104789 (FMO4)

Protein Structure

UniProt Annotation

Function

This protein is involved in the oxidative metabolism of a variety of xenobiotics such as drugs and pesticides.

Subcellular Localization

Microsome membrane. Endoplasmic reticulum membrane.

Disease Associations

Tissue Specificity

Liver.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004499	N,N-dimethylaniline monooxygenase activity
GO:0016491	oxidoreductase activity
GO:0050660	flavin adenine dinucleotide binding
GO:0050661	NADP binding

Biological Process

GO:0042737	drug catabolic process
GO:0055114	oxidation-reduction process

Cellular Component

GO:0005789	endoplasmic reticulum membrane
GO:0016021	integral component of membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000960 Flavin monooxygenase FMO
IPR002253 Flavin monooxygenase (FMO) 1
IPR002255 Flavin monooxygenase (FMO) 3
IPR002256 Flavin monooxygenase (FMO) 4
IPR012143 Dimethylaniline monooxygenase, N-oxide-forming
IPR020946 Flavin monooxygenase-like
IPR023753 Pyridine nucleotide-disulphide oxidoreductase, FAD/NAD(P)-binding domain

PFAM

PF00743
PF07992

PRINTS

PR00370
PR01121
PR01123
PR01124

PIRSF

PIRSF000332

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt