Version 5.4
Homo sapiens Protein: RFWD2
Summary
InnateDB Protein IDBP-104999.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RFWD2
Protein Name ring finger and WD repeat domain 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000356638
InnateDB Gene IDBG-104993 (RFWD2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 96 experimentally validated interaction(s) in this database.
They are also associated with 6 interaction(s) predicted by orthology.
Experimentally validated
Total 96 [view]
Protein-Protein 95 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 6 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008270 zinc ion binding
Biological Process
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005925 focal adhesion
Protein Structure and Domains
PDB ID
InterPro IPR001680 WD40 repeat
IPR001841 Zinc finger, RING-type
IPR017986 WD40-repeat-containing domain
PFAM PF00400
PF13639
PF14634
PRINTS
PIRSF
SMART SM00320
SM00184
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H0Y339
UniProt Splice Variant
Entrez Gene 64326
UniGene Hs.670708
RefSeq
HUGO HGNC:17440
OMIM 608067
CCDS
HPRD 07455
IMGT
EMBL AK001278 AL162736 AL359265 AL513329 AL590723
GenPept BAG50884

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca