Version 5.4
Homo sapiens Protein: LHX9
Summary
InnateDB Protein IDBP-105588.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol LHX9
Protein Name LIM homeobox 9
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000356360
InnateDB Gene IDBG-105584 (LHX9)
Protein Structure
UniProt Annotation
Function Involved in gonadal development. {ECO:0000250}.
Subcellular Localization Nucleus {ECO:0000255PROSITE- ProRule:PRU00108}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
They are also associated with 7 interaction(s) predicted by orthology.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 7 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003677 DNA binding
GO:0003700 sequence-specific DNA binding transcription factor activity
GO:0003714 transcription corepressor activity
GO:0008270 zinc ion binding
GO:0043565 sequence-specific DNA binding
Biological Process
GO:0008045 motor neuron axon guidance
GO:0045892 negative regulation of transcription, DNA-templated
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR001356 Homeobox domain
IPR001781 Zinc finger, LIM-type
IPR009057 Homeodomain-like
PFAM PF00046
PF00412
PRINTS
PIRSF
SMART SM00389
SM00132
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9NQ69
PhosphoSite PhosphoSite-Q9NQ69
TrEMBL
UniProt Splice Variant
Entrez Gene 56956
UniGene Hs.739524
RefSeq NP_001014434
HUGO HGNC:14222
OMIM 606066
CCDS CCDS30962
HPRD 07299
IMGT
EMBL AJ277915 AJ277916 AJ277917 AJ277918 AJ277919 AJ277920 AJ296272 AL590115 AY273889 BC131622 CH471067
GenPept AAI31623 AAP32471 CAB97493 CAB98128 CAC33174 CAH71760 CAH71761 CAH71763 CAH71764 EAW91290 EAW91292

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca